When it comes to cancer immunotherapy or immuno-oncology, it helps in the investigation of how the human immune system responds to cancer, how its cells spread in the body, and how the human immune system can be used to battle the effects of cancer. This is where flow cytometry comes into play, and which leverages a versatile and robust technology to perform such research. It helps in the study of the detailed analysis of human cell signaling and activities. According to an article published on https://www.ncbi.nlm.nih.gov, cell sorting and cytometry are one of the best technologies used in the biomedical study and clinical diagnostics. Read on to learn more about it in this article.
Human immunity protects us from ailments and toxic elements such as bacteria, abnormal cancerous cells, and viruses. When it comes to cancer, the task of the human immune system is to battle the abnormal cells and destroy them. Then, these cells may find their way to avoid the immune system, thus letting the cancerous cells to expand and spread. That is why immuno-oncology is so important. The research in this field helps in finding treatment options that work with the immune system so that the body functions normally to battle life-threatening cancer.
Focus on cell study
The study related to immuno-oncology focuses primarily on the study of cells. Their kinds and how do they behave when a patient has cancer. Flow cytometry is used to probe these cells, a process that helps in the research. The procedure lets you recognize cellular markers via intercellular staining or surface staining methods. The markers are used further to spot various types of cells. These methods come useful when developing cell-oriented therapies. Let us cite an example to explain this point in a better way. CD4 is the typical marker for T cell subsets that are found on natural killer cells, macrophages, and lymphoid cells. The process entails the activation of the T cell and then offers a foundation for the T cell therapies battling cancer.
Study of the heterogeneous cell population
If cytometry is used to make a study of the heterogeneous cell population, it will evaluate the various subpopulations in a couple of minutes. The method is quicker than the other options. Besides, the volume of data generated is elaborate, and the assessment incorporates the ratio of red cells in comparison to the green cells. It provides additional information on dull green and bright green cells too.
Identifies things that other methods fail
When you use flow cytometry to look at a uniform population of cells, it has an advantage of highlighting the non-uniformities as well. It gets rid of the debris or dead cells when providing you with the final data. The method is 100 percent accurate and beats all other alternative techniques. Besides, cytometry effortlessly amalgamates into immuno-oncology.
With cytometry, researchers can analyze thousands of microscopic particles each second. The method is useful in the healthcare sector and helps in the study and analysis of blood cancer. It helps in understanding the complexity of the human immune response.
Author Bio –
Kristen Smith is a health expert who has been running many health seminars and public discussions. She also manages her blog and reviews the health-related details provided by authentic sources. You can visit cytometry for more information.